Sources Avery, Oswald T. MacLeod, and Maclyn McCarty. Berta, Phillippe, J. Ross Hawkins, Andrew H. Sinclair, Anne Taylor, Beatrice L. Griffiths, Peter N. Goodfellow, and Marc Fellous. Boveri, Theodor. Capel, Blanche, Kenneth H. Albrecht, Linda L.
Washburn, and Eva M. Gilbert, Scott. Developmental Biology , 8th edition. Sunderland: Sinauer Associates, Novus Biologicals proteins and lysates for SRY. Abcam proteins for SRY. Browse Sino Biological Assays. Belongs to the SRY family. Family: Belongs to the SRY family. OriGene clones in human , mouse , rat for SRY. Addgene plasmids for SRY. Signaling by Wnt. Androgen Signaling. Deactivation of the beta-catenin transactivating complex.
Signal Transduction. Regulation of Androgen receptor activity. Is activated by: WT1. Browse compounds at ApexBio. This gene is overexpressed in Testis x Germ Layers: ectoderm endoderm mesoderm.
Systems: endocrine immune integumentary nervous reproductive skeletal muscle skeleton urinary. Regions: Head and neck: brain head hypothalamus pituitary gland.
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References 1 Sinclair, A. View author publications. Rights and permissions Reprints and Permissions. About this article Cite this article Berta, P. Copy to clipboard. Prokop , Surya B. Chhetri , J. Underwood , Katie Uhl , Melinda R. Biochem Biophys Res Commun — Kashimada K, Koopman P Sry: the master switch in mammalian sex determination. Development — Katoh K, Miyata T A heuristic approach of maximum likelihood method for inferring phylogenetic tree and an application to the mammalian SOX-3 origin of the testis-determining gene SRY.
FEBS Lett — Kondoh H, Kamachi Y SOX-partner code for cell specification: regulatory target selection and underlying molecular mechanisms. Nature — J Genet Genomics — Novartis Found Symp —18, discussion , , Hum Mol Genet — Oncogene — Nucleic Acids Res — Biol Reprod — Parma P, Radi O, Vidal V et al R-spondin1 is essential in sex determination, skin differentiation and malignancy.
Genomics — Frustrated induced fit in a bent protein—DNA complex. J Biol Chem. Biol Cell — Mol Hum Reprod — Mol Cell Endocrinol — Mol Cell Biochem — Trends Endocrinol Metab — J Clin Invest — Biochim Biophys Acta — Physiol Rev — Curr Opin Genet Dev — Download references. We thank Terje Svingen and Josephine Bowles for critical reading of the manuscript.
You can also search for this author in PubMed Google Scholar. Correspondence to Peter Koopman. Reprints and Permissions. Zhao, L. SRY protein function in sex determination: thinking outside the box. Chromosome Res 20, —
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