Mohs, M. Initially, Dr. Mohs removed tumors with a chemosurgical technique where thin layers of tissue were excised and pathologically examined after application of zinc chloride paste. He developed a unique technique of color-coding excised specimens and created a mapping process to accurately identify the location of remaining cancerous cells.
After Dr. Theodore Tromovitch's paper detailing microscopically controlled excision with fresh unfixed tissue was published, Dr. Mohs and most other chemosurgeons of the day began to use the fresh tissue technique almost exclusively. Patients were the primary beneficiaries of this change because they could now have their surgeries and closures in one visit on the same day, allowing for immediate reconstruction of the wound.
This change eventually brought about a name change from Chemosurgery to Mohs Micrographic Surgery. In the s, specific machines called cryostats were developed to assist the process of freezing live tissue for examination under a microscope. Automatic tissue staining machines were added in the s to assist clinics with the growing number of patients and tissue samples. Throughout all the technical improvements in devices and refinements of technique, the focal point—the color-coded mapping of excised specimens and their thorough microscopic examination—remains the defining characteristic of Mohs micrographic surgery to this day.
It chronicles the creation of the American College of Chemosurgery by Dr. Frederic Mohs and his contemporaries 50 years ago, as well as the evolution and growth of the organization and of Mohs surgery, including the perspectives of 10 important figures from founding to present. We use cookies to ensure you the best experience on our website. Your acceptance helps ensure that experience happens. To learn more, please visit our Privacy Notice.
American College of Mohs Surgery. Click here to order your copy! Cookie Notice. However, in , it is said that he performed a fresh tissue excision by accident, and was so surprised with the enhanced results that he changed his technique.
Most chemosurgeons changed to the fresh tissue method soon afterwards as the new method had the benefit of allowing full excision and closing of the wound on the same day. The Mohs surgery technique was improved in the s by Perry Robins, who introduced the idea of using a local anaesthetic and then freezing the excised tissue ready for examination.
Although Mohs chemical paste is no longer part of the technique, the term chemosurgery is still sometimes used to refer to Mohs microsurgery. While Frederic Mohs was the pioneer and lifelong advocate of his famous technique, he has enjoyed the support and inspiration of many leading scientists along the way.
These include his original mentor, the zoologist Dr Michael Guyer, Bob Patnaude, his trusted technician of almost 40 years, and Dr Theodore Tromovitch, who published a revolutionary paper on fresh, unfixed tissue excision. Frederic Mohs died in aged 92, having dramatically improved the outcome for countless skin cancer patients around the world. Your email address will not be published.
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